Nicole Seegers: search on Z-Library

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1

Optimized Target Residence Time: Type I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine

Wentsch, Heike K., Walter, Niklas M., Bührmann, Mike, Mayer-Wrangowski, Svenja, Rauh, Daniel, Zaman, Guido J. R., Willemsen-Seegers, Nicole, Buijsman, Rogier C., Henning, Melanie, Dauch, Daniel, Zende

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

2

Target residence time-guided optimization on TTK kinase results in inhibitors with potent anti-proliferative activity

Uitdehaag, Joost C.M., de Man, Jos, Willemsen-Seegers, Nicole, Prinsen, Martine B.W., Libouban, Marion A.A., Sterrenburg, Jan Gerard, de Wit, Joeri J.P., de Vetter, Judith R.F., de Roos, Jeroen A.D.M.

Journal:

Journal of Molecular Biology

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

3

Hedging under model misspecification: All risk factors are equal, but some are more equal than others …

Nicole Branger, Eva Krautheim, Christian Schlag, Norman Seeger

Journal:

Journal of Futures Markets

Year:

2012

Language:

english

File:

PDF, 11.60 MB

english, 2012

4

Using Hedging Errors to Identify Option Pricing Models

Branger, Nicole, Schlag, Christian, Schneider, Eva, Seeger, Norman

Journal:

SSRN Electronic Journal

Year:

2007

Language:

english

File:

PDF, 768 KB

english, 2007

5

Impact of Vibration and Agitation Speed on Dissolution of USP Prednisone Tablets RS and Various IR Tablet Formulations

Seeger, Nicole, Lange, Sigrid, Klein, Sandra

Journal:

AAPS PharmSciTech

Year:

2015

Language:

english

File:

PDF, 817 KB

english, 2015

6

Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension andBMPR2mutations

Nicole Pfarr, Justyna Szamalek-Hoegel, Christine Fischer, Katrin Hinderhofer, Christian Nagel, Nicola Ehlken, Henning Tiede, Horst Olschewski, Frank Reichenberger, Ardeschir HA Ghofrani, Werner Seeger

Journal:

Respiratory Research

Year:

2011

Language:

english

File:

PDF, 490 KB

english, 2011

7

Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158

Grobben, Yvonne, Uitdehaag, Joost C.M., Willemsen-Seegers, Nicole, Tabak, Werner W.A., Man, Jos de, Buijsman, Rogier C., Zaman, Guido J.R.

Journal:

Journal of Structural Biology: X

Year:

2019

File:

PDF, 1.89 MB

2019

8

Follow-Up (Measurement) of Corrected QT Interval in Adult Patients before and after Lung Transplantation

Bandorski, Dirk, Hoeltgen, Reinhard, Becker, Nicole, Padberg, Winfried, Bogossian, Harilaos, Wiedenroth, Christoph, Arlt, Matthias, Hamm, Christian, Seeger, Werner, Ghofrani, Hossein Ardeschir, Hecker

Journal:

BioMed Research International

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

9

Stem cell compartmentalization in diabetes and high cardiovascular risk reveals the role of DPP-4 in diabetic stem cell mobilopathy

Fadini, Gian Paolo, Albiero, Mattia, Seeger, Florian, Poncina, Nicol, Menegazzo, Lisa, Angelini, Annalisa, Castellani, Chiara, Thiene, Gaetano, Agostini, Carlo, Cappellari, Roberta, Boscaro, Elisa, Ze

Journal:

Basic Research in Cardiology

Year:

2013

Language:

english

File:

PDF, 2.29 MB

english, 2013

10

Robustness of Barrier Membrane Coated Metoprolol Tartrate Matrix Tablets: Drug Release Evaluation under Physiologically Relevant in vitro Conditions

Klein, Sandra, Seeger, Nicole, Mehta, Raxit, Missaghi, Shahrzad, Grybos, Relindis, Rajabi-Siahboomi, Ali

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

11

Nationwide Analysis on Surgical Staging Procedures and Systemic Treatment for Patients With Endometrial Cancer in Germanionwide Analysis on Surgical Staging Procedures and Systemic Treatment for Patients With Endometrial Cancer in Germany

Battista, Marco Johannes, Steiner, Eric, Rieks, Nicole, Steetskamp, Joscha, Seeger, Alexander, Sicking, Isabel, Böhm, Daniel, Schmidt, Marcus, Koelbl, Heinz

Journal:

International Journal of Gynecological Cancer

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

12

SiO 2 -coated carbon nanotubes: theory and experiment

Seeger, Torsten, Cöhler, Thomas, Frauenheim, Thomas, Grobert, Nicole, Terrones, Mauricio, Seifert, Gotthard, Rühle, Manfred

Journal:

Zeitschrift für Metallkunde

Year:

2002

Language:

english

File:

PDF, 628 KB

english, 2002

13

Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface

Nicole Monroe, Gaby Sennhauser, Markus A. Seeger, Christophe Briand, Markus G. Grütter

Journal:

Journal of Structural Biology

Year:

2011

Language:

english

File:

PDF, 3.06 MB

english, 2011

14

Optimierte Bindungsdauer am Zielenzym: Typ-I1/2 -Inhibitoren der p38α-MAP-Kinase mit verbesserter Bindungskinetik durch direkte Interaktion mit der R-Spine

Wentsch, Heike K., Walter, Niklas M., Bührmann, Mike, Mayer-Wrangowski, Svenja, Rauh, Daniel, Zaman, Guido J. R., Willemsen-Seegers, Nicole, Buijsman, Rogier C., Henning, Melanie, Dauch, Daniel, Zende

Journal:

Angewandte Chemie

Year:

2017

Language:

german

File:

PDF, 2.46 MB

german, 2017

15

The Healthy Start project: a randomized, controlled intervention to prevent overweight among normal weight, preschool children at high risk of future overweight

Nanna Julie Olsen, Tine Buch-Andersen, Mina Nicole Händel, Louise Mai Østergaard, Jeanett Pedersen, Charlotte Seeger, Maria Stougaard, Maria Trærup, Kate Livemore, Erik Lykke Mortensen, Claus Holst, B

Journal:

BMC Public Health

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

16

Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance

Willemsen-Seegers, Nicole, Uitdehaag, Joost C.M., Prinsen, Martine B.W., de Vetter, Judith R.F., de Man, Jos, Sawa, Masaaki, Kawase, Yusuke, Buijsman, Rogier C., Zaman, Guido J.R.

Journal:

Journal of Molecular Biology

Year:

2017

Language:

english

File:

PDF, 965 KB

english, 2017

17

ω-3 Fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation

Mayer, Konstantin, Merfels, Martina, Muhly-Reinholz, Marion, Gokorsch, Stephanie, Rosseau, Simone, Lohmeyer, Jürgen, Schwarzer, Nicole, Krüll, Matthias, Suttorp, Norbert, Grimminger, Friedrich, Seeger

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

18

Design, Synthesis and Biological Evaluation of Novel Type I½ p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency and Prolonged Target Residence Time by Interfering with the R Spine

Walter, Niklas M., Wentsch, Heike K., Bührmann, Mike, Bauer, Silke M, Döring, Eva, Mayer-Wrangowski, Svenja, Sievers-Engler, Adrian, Willemsen-Seegers, Nicole, Zaman, Guido, Buijsman, Rogier, Lämmerho

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.39 MB

english, 2017

19

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple negative breast cancer model

Maia, Ana R. R., de Man, Jos, Boon, Ute, Janssen, Aniek, Song, Ji-Ying, Omerzu, Manja, Sterrenburg, Jan Gerard, Prinsen, Martine B.W., Willemsen-Seegers, Nicole, de Roos, Jeroen A.D.M., van Doornmalen

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

20

Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines

Schmidt, Franziska, Boltze, Johannes, Jäger, Carsten, Hofmann, Sarah, Willems, Nicole, Seeger, Johannes, Härtig, Wolfgang, Stolzing, Alexandra

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2015

Language:

english

File:

PDF, 776 KB

english, 2015

21

Combined cellular and biochemical profiling to identify predictive drug response biomarkers for kinase inhibitors approved for clinical use between 2013 and 2017

Uitdehaag, Joost C.M., Kooijman, Jeffrey J., de Roos, Jeroen A.D.M., Prinsen, Martine B.W., Dylus, Jelle, Willemsen-Seegers, Nicole, Kawase, Yusuke, Sawa, Masaaki, de Man, Jos, van Gerwen, Suzanne J.C

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 16.99 MB

english, 2018

22

First Report of Bacterial Wilt Caused by Ralstonia solanacearum Phylotype IIB Sequevar 1 affecting tomato in different Regions of Chile

Vasconez, Ingrid Nicole, Besoain, Ximena A., Vega-Celedon, Paulina, Valenzuela, Miryam, Seeger, Michael

Journal:

Year:

2020

Language:

english

File:

PDF, 109 KB

english, 2020

23

Structure-based lead identification of ATP-competitive MK2 inhibitors

Tjeerd Barf, Allard Kaptein, Sander de Wilde, Ruud van der Heijden, Richard van Someren, Dennis Demont, Carsten Schultz-Fademrecht, Judith Versteegh, Mario van Zeeland, Nicole Seegers, Bert Kazemier,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 656 KB

english, 2011

24

Cytochrome P450 epoxygenaseâderived 5,6âepoxyeicosatrienoic acid relaxes pulmonary arteries in normoxia but promotes sustained pulmonary vasoconstriction in hypoxia

Strielkov, Ievgen, Catherine Krause, Nicole, Knoepp, Fenja, Alebrahimdehkordi, Nasim, Pak, Oleg, Garcia, Claudia, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo, Seeger, Werner, Grimminger, Friedr

Journal:

Acta Physiologica

Year:

2020

File:

PDF, 1.19 MB

2020

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